abstract：OBJECTIVE:To compare fast versus slow switching from stimulants to atomoxetine (ATX) in children and adolescents with attention-deficit/hyperactivity disorder (ADHD). METHODS:This was a randomized, controlled, open-label study in 6-16-year-old ADHD patients, previously treated with stimulants and cross-titrated (fast ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Cardo E,Porsdal V,Quail D,Fuentes J,Steer C,Montoya A,Anand E,Escobar R

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:The purpose of this article was to systematically review the literature on stimulant and atomoxetine combination therapy, in particular: 1) Characteristics of patients with attention-deficit/hyperactivity disorder (ADHD) given combination therapy, 2) treatment strategies used, 3) efficacy and effectiveness, a...

journal_title：Journal of child and adolescent psychopharmacology

authors： Treuer T,Gau SS,Méndez L,Montgomery W,Monk JA,Altin M,Wu S,Lin CC,Dueñas HJ

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:Abnormal prefrontal and subcortical activity during cognitive control tasks is identified in non-depressed adolescents with bipolar disorder (BD); however, little is known about the neural correlates of bipolar adolescents in a depressed state (BDd). We aimed to investigate baseline versus after-treatment pat...

journal_title：Journal of child and adolescent psychopharmacology

authors： Diler RS,Segreti AM,Ladouceur CD,Almeida JR,Birmaher B,Axelson DA,Phillips ML,Pan L

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:Few studies of psychotropic medication use among children and adolescents address the effectiveness of this medication, as it is typically used in naturalistic treatment settings. The objective of this study was to investigate psychotropic medication use among children and adolescents treated in system of car...

journal_title：Journal of child and adolescent psychopharmacology

authors： Drilea SK,Jowers K,Lichtenstein C,Hale M,Blau G,Stromberg S

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the efficacy and safety of acute quetiapine monotherapy in adolescents with schizophrenia. METHODS:Patients ages 13-17 years with an American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, 4th ed., Text Revision (DSM-IV-TR) diagnosis ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Findling RL,McKenna K,Earley WR,Stankowski J,Pathak S

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:Edivoxetine (LY2216684) is a selective and potent norepinephrine reuptake inhibitor (NERI). The pharmacokinetics (PK) and pharmacodynamics (PD) of edivoxetine were assessed in children and adolescent patients with attention-deficit/hyperactivity disorder (ADHD) following single and once-daily oral doses of ed...

journal_title：Journal of child and adolescent psychopharmacology

authors： Kielbasa W,Quinlan T,Jin L,Xu W,Lachno DR,Dean RA,Allen AJ

更新日期：2012-08-01 00:00:00

abstract：:Although sensory deficits are frequently observed in autistic individuals, pharmacologic interventions targeting these abnormalities are lacking. The goal of this investigation was to assess the effectiveness of aripiprazole in targeting sensory deficits in children and adolescents with autism. Using an outpatient cli...

journal_title：Journal of child and adolescent psychopharmacology

authors： Fung LK,Chahal L,Libove RA,Bivas R,Hardan AY

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To examine the persistence of three newly initiated stimulant preparations among Medicaid children and adolescents with attention-deficit/hyperactivity disorder (ADHD) diagnosis. METHODS:A retrospective longitudinal claims analysis was conducted by using Medicaid analytical eXtract data of four states. The s...

journal_title：Journal of child and adolescent psychopharmacology

authors： Palli SR,Kamble PS,Chen H,Aparasu RR

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:Studies have primarily focused on adverse life events (ALEs) as potential causes rather than as outcomes of pediatric depression. The current study prospectively examines ALEs in a sample of youth with attention-deficit/hyperactivity disorders (ADHD) to determine whether having a major depressive disorder (M...

journal_title：Journal of child and adolescent psychopharmacology

authors： Daviss WB,Diler R

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:Methylphenidate (MPH) is commonly used to treat attention-deficit/hyperactivity disorder (ADHD) in all children, including those with velocardiofacial syndrome (VCFS). Yet concerns have been raised regarding its safety and efficacy in VCFS. The goal of this study was to examine the safety and efficacy of MPH ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Green T,Weinberger R,Diamond A,Berant M,Hirschfeld L,Frisch A,Zarchi O,Weizman A,Gothelf D

更新日期：2011-12-01 00:00:00

abstract：:Risperidone has been shown to improve serious behavioral problems in children with autism. Here we asked whether risperidone-associated improvement was related to changes in concentrations of inflammatory molecules in the serum of these subjects. Seven molecules were identified as worthy of further assessment by perfo...

journal_title：Journal of child and adolescent psychopharmacology

authors： Tobiasova Z,van der Lingen KH,Scahill L,Leckman JF,Zhang Y,Chae W,McCracken JT,McDougle CJ,Vitiello B,Tierney E,Aman MG,Arnold LE,Katsovich L,Hoekstra PJ,Volkmar F,Bothwell AL,Kawikova I

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Psychostimulants are effective treatments for attention-deficit/hyperactivity disorder (ADHD) but may be associated with euphoric effects, misuse/diversion, and adverse effects. These risks are perceived by some clinicians to be greater in substance-abusing adolescents relative to non-substance-abusing adults...

journal_title：Journal of child and adolescent psychopharmacology

authors： Winhusen TM,Lewis DF,Riggs PD,Davies RD,Adler LA,Sonne S,Somoza EC

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:The rate-corrected QT interval (QTc) prolongation is a risk factor for sudden cardiac death and may be induced by antipsychotic drugs. OBJECTIVE:To determine the clinical characteristics associated with QTc prolongation (440 msec or greater) in children and adolescents hospitalized for treatment of psychiat...

journal_title：Journal of child and adolescent psychopharmacology

authors： Correll CU,Harris J,Figen V,Kane JM,Manu P

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:The present study examined the course of ADHD over 24 months in a preschool population. METHOD:n=48 preschoolers with ADHD, aged 3.0-5.11 years, subjects included in a larger sample of preschoolers with depression and other disorders (n=306) were comprehensively assessed at 3 annual time points over 24 month...

journal_title：Journal of child and adolescent psychopharmacology

authors： Tandon M,Si X,Luby J

更新日期：2011-08-01 00:00:00

abstract：:Bipolar disorder (BP) in youth is an impairing psychiatric disorder associated with high rates of relapse and recurrence. High rates of psychiatric and medical co-morbidities account for additional illness burden in pediatric BP. The elevated risk of overweight and obesity in this population is of particular concern. ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Goldstein TR,Goldstein BI,Mantz MB,Bailey B,Douaihy A

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:To assess the effect of Osmotic-Release Oral System (OROS) methylphenidate (MPH) on a variety of measures evaluating academic performance, cognition, and social behavior in children with attention-deficit/hyperactivity disorder (ADHD). METHODS:This double-blind, randomized, placebo-controlled, crossover labo...

journal_title：Journal of child and adolescent psychopharmacology

authors： Wigal SB,Wigal T,Schuck S,Brams M,Williamson D,Armstrong RB,Starr HL

更新日期：2011-04-01 00:00:00

abstract：:The study assessed competencies and practices of a large group of healthcare providers in childhood attention-deficit/hyperactivity disorder (ADHD), and identified barriers to improving care. Methods were self-assessment using an Internet questionnaire with a standardized patient case; analysis compared with professio...

journal_title：Journal of child and adolescent psychopharmacology

authors： Brown JJ,Hertzer JL,Findling RL

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to present the reliability and validity of the Children's Depression Rating Scale-Revised (CDRS-R) in the adolescent age group. METHOD:Adolescents with symptoms of depression were assessed using the CDRS-R and global severity and functioning scales at screening, baseline, and after ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Mayes TL,Bernstein IH,Haley CL,Kennard BD,Emslie GJ

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:This functional magnetic resonance imaging (fMRI) study investigated the effects of pharmacotherapy on brain function underlying affect dysregulation and cognitive function in pediatric bipolar disorder (PBD). METHOD:Healthy controls (HC) (n=14; mean age =14.1 ± 2.4 years) and unmedicated PBD patients with m...

journal_title：Journal of child and adolescent psychopharmacology

authors： Pavuluri MN,Passarotti AM,Parnes SA,Fitzgerald JM,Sweeney JA

更新日期：2010-10-01 00:00:00

abstract：:Obsessive-compulsive disorder (OCD) and related conditions including Tourette's disorder (TD) are chronic, relapsing disorders of unknown etiology associated with marked impairment and disability. Associated immune dysfunction has been reported and debated in the literature since the late 80s. The immunologic culprit ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Murphy TK,Kurlan R,Leckman J

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Still little is known about neuropsychological differences between boys and girls with attention-deficit/hyperactivity disorder (ADHD) and whether there are sex-specific differences in the modulation of attentional performance by methylphenidate (MPH). METHOD:In this study, 27 males and 27 females between 8...

journal_title：Journal of child and adolescent psychopharmacology

authors： Günther T,Herpertz-Dahlmann B,Konrad K

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to analyze changes in the prevalence and incidence of antidepressant use among children and adolescents in Finland post October, 2003. METHOD:The sample comprised all children and adolescents in Finland aged < or =19.0 years (n = 27,676) who collected one or more reimbursed prescrip...

journal_title：Journal of child and adolescent psychopharmacology

authors： Foulon V,Svala A,Koskinen H,Chen TF,Saastamoinen LK,Bell JS

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:Guanfacine has been shown to reduce hyperactive behaviors in children with attention-deficit/hyperactivity disorder (ADHD) and possibly in children with pervasive developmental disorder (PDD) and hyperactivity. The aim of this exploratory study was to examine whether gene variants encoding the multidrug resis...

journal_title：Journal of child and adolescent psychopharmacology

authors： McCracken JT,Aman MG,McDougle CJ,Tierney E,Shiraga S,Whelan F,Arnold LE,Posey D,Ritz L,Vitiello B,Scahill L

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to conduct a prospective safety and tolerability study of aripiprazole for the treatment of tics in children and adolescents with Tourette's disorder (TD). METHOD:Eleven subjects (10 males) with TD (age 9-19 years, mean 13.36, standard deviation [SD] 3.33) who did not respond or wer...

journal_title：Journal of child and adolescent psychopharmacology

authors： Lyon GJ,Samar S,Jummani R,Hirsch S,Spirgel A,Goldman R,Coffey BJ

更新日期：2009-12-01 00:00:00

abstract：INTRODUCTION:This study compared two atomoxetine titration dosing schedules and two atomoxetine maintenance doses for treating adolescent attention-deficit/hyperactivity disorder (ADHD) inattention and hyperactivity/impulsivity. METHODS:Adolescents (N = 267) were randomized to a slow or fast titration schedule. Patien...

journal_title：Journal of child and adolescent psychopharmacology

authors： Wietecha LA,Williams DW,Herbert M,Melmed RD,Greenbaum M,Schuh K

更新日期：2009-12-01 00:00:00

abstract：:In clinical samples, juvenile bipolar disorder (JBPD) is frequently accompanied by co-morbid attention-deficit/hyperactivity disorder (ADHD). Clinical trials assessing combined psychopharmacological interventions in this population are scarce, and methylphenidate (MPH) may worsen manic symptoms. We conducted a randomi...

journal_title：Journal of child and adolescent psychopharmacology

authors： Zeni CP,Tramontina S,Ketzer CR,Pheula GF,Rohde LA

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to examine the association between the CYP2D6 and CYP2C19 genotype-predicted combined phenotypes and short-term measures of psychotropic efficacy and toxicity. METHODS:A rater-blinded, retrospective genotype association design examined a cohort of hospitalized pediatric psychiatric ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Prows CA,Nick TG,Saldaña SN,Pathak S,Liu C,Zhang K,Daniels ZS,Vinks AA,Glauser TA

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to demonstrate the superior efficacy of atomoxetine with respect to placebo and to compare parent and child perceptions of health-related quality of life (HRQoL). METHOD:This randomized, placebo-controlled, 12-week parallel clinical trial included 151 untreated children/adolescents ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Escobar R,Montoya A,Polavieja P,Cardo E,Artigas J,Hervas A,Fuentes J

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to examine the prevalence of activation cluster adverse events (AC-AEs) in youths treated with the selective serotonin reuptake inhibitor (SSRI) fluvoxamine for anxiety and the relationship of AC-AEs to SSRI blood levels. METHODS:Data from the Research Units on Pediatric Psychopharm...

journal_title：Journal of child and adolescent psychopharmacology

authors： Reinblatt SP,DosReis S,Walkup JT,Riddle MA

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVES:Previous studies have suggested that the sum of Attention, Aggression, and Anxious/Depressed subscales of Child Behavior Checklist (CBCL-PBD; pediatric bipolar disorder phenotype) may be specific to pediatric bipolar disorder (BP). The purpose of this study was to evaluate the usefulness of the CBCL and CBCL...

journal_title：Journal of child and adolescent psychopharmacology

authors： Diler RS,Birmaher B,Axelson D,Goldstein B,Gill M,Strober M,Kolko DJ,Goldstein TR,Hunt J,Yang M,Ryan ND,Iyengar S,Dahl RE,Dorn LD,Keller MB

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:Co-occurrence of substance use and bipolar disorders is both common and associated with poor treatment response and greater functional impairment than either disorder alone. The neurophysiological correlates of this co-morbidity however, remain unclear. In this pilot study, we compared brain morphometry betwe...

journal_title：Journal of child and adolescent psychopharmacology

authors： Jarvis K,DelBello MP,Mills N,Elman I,Strakowski SM,Adler CM

更新日期：2008-12-01 00:00:00

abstract：:Treatment with psychostimulant medication has been shown to improve scholastic functioning in children with attention-deficit/hyperactivity disorder (ADHD). However, the extent to which long-term academic gains are apparent in those having received such treatment remains elusive. This study examined prospectively the ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Powers RL,Marks DJ,Miller CJ,Newcorn JH,Halperin JM

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:A recent 12-week controlled comparison demonstrated the superiority of clozapine to "high-dose" olanzapine in adolescents with treatment-refractory schizophrenia. In the present study, the authors conducted a 12-week, open-label, follow-up study to examine changes in lipid and glucose metabolism in youths mai...

journal_title：Journal of child and adolescent psychopharmacology

authors： Kumra S,Kranzler H,Gerbino-Rosen G,Kester HM,DeThomas C,Cullen K,Regan J,Kane JM

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:Although recent studies and meta-analyses confirm the efficacy of antidepressants in the acute phase of treatment for adolescent depression, there are few data available to allow assessment of the value of continued use of antidepressants in depressed adolescents after acute response. This study examines the ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Cheung A,Kusumakar V,Kutcher S,Dubo E,Garland J,Weiss M,Kiss A,Levitt A

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:This study's goal was to determine among youths with attention-deficit/hyperactivity disorder (ADHD) how the history of ADHD pharmacotherapy influenced the risk of developing major depressive disorder (MDD), compared to other commonly reported predictors. METHOD:Diagnostic and treatment history data were ana...

journal_title：Journal of child and adolescent psychopharmacology

authors： Daviss WB,Birmaher B,Diler RS,Mintz J

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:The striatum, including the putamen and caudate, plays an important role in executive and emotional processing and may be involved in the pathophysiology of mood disorders. Few studies have examined structural abnormalities of the striatum in pediatric major depressive disorder (MDD) patients. We report stria...

journal_title：Journal of child and adolescent psychopharmacology

authors： Matsuo K,Rosenberg DR,Easter PC,MacMaster FP,Chen HH,Nicoletti M,Caetano SC,Hatch JP,Soares JC

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:This study evaluates pediatric antidepressant prescribing practices of Nebraska clinicians. METHODS:Surveys were sent in July, 2005, to 1,521 prescribing clinicians throughout Nebraska to assess pediatric antidepressant use along with any practice changes following the U.S. Food and Drug Administration (FDA)...

journal_title：Journal of child and adolescent psychopharmacology

authors： Bhatia SK,Rezac AJ,Vitiello B,Sitorius MA,Buehler BA,Kratochvil CJ

更新日期：2008-02-01 00:00:00

abstract：INTRODUCTION:The antipsychotic drugs are the best-studied agents shown to reduce symptoms in autism, including hyperactivity, aggression, self-abusive behavior, temper tantrums, lability, irritability, social withdrawal, and stereotypical behaviors. However, significant weight gain has been associated with use of many ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Malone RP,Delaney MA,Hyman SB,Cater JR

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to examine immediate-release methylphenidate effectiveness during the 10-month open-label continuation phase of the Preschoolers with Attention-Deficit/Hyperactivity Disorder (ADHD) Treatment Study (PATS). METHODS:One hundred and forty preschoolers with ADHD, who had improved with a...

journal_title：Journal of child and adolescent psychopharmacology

authors： Vitiello B,Abikoff HB,Chuang SZ,Kollins SH,McCracken JT,Riddle MA,Swanson JM,Wigal T,McGough JJ,Ghuman JK,Wigal SB,Skrobala AM,Davies M,Posner K,Cunningham C,Greenhill LL

更新日期：2007-10-01 00:00:00

abstract：:This meta-analysis assessed aggression and/or hostility-related events in children and adolescents treated with fluoxetine (n = 376) compared with placebo (n = 255). Aggression and/or hostility-related events were identified in 2.1% of fluoxetine versus 3.1% of placebo-treated patients (p = 0.588). This analysis fails...

journal_title：Journal of child and adolescent psychopharmacology

authors： Tauscher-Wisniewski S,Nilsson M,Caldwell C,Plewes J,Allen AJ

更新日期：2007-10-01 00:00:00